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PAGE 24
In this 1804 letter to the Mayor and Municipal Council, Governor Claiborne transmitted the alarming news from Dr. Watkins, the physician of the port (and later Mayor of New Orleans) that small pox, earlier detected on board ships downriver, had reached the city itself. But the Governor took comfort in the fact that a supply of small pox vaccine was available to help prevent a serious outbreak of the dreaded disease. The accompanying letter from Dr. Watkins explained that small pox was discovered in a "Negro man" admitted to the Charity Hospital and speculated that the victim may have been "clandestinely introduced from on board some vessel."

The small pox vaccine (actually an injection of the less serious disease cow pox) had only been discovered by British physician William Jenner in 1796; it was introduced into New England in 1800 and reached the Southern colonies a few years later. When smallpox appeared in the city in 1804, Governor Claiborne strongly supported the use of the new vaccine over the older form of inoculation or variolation (which involved deliberate exposure to smallpox itself), and, as a result, a major epidemic was averted.
     [Conseil de Ville. Letters, Petitions and Reports, #506]

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